|
KMID : 0043319850080040221
|
|
Archives of Pharmacal Research
1985 Volume.8 No. 4 p.221 ~ p.227
|
|
|
Studies on Triterpenoid Corticomimetics (IV) E-Ring Opending of Pormolic Acid by Retrograde Aldol Condensation
|
|
Han YN
Han BH/Park ET/Kim TH
|
|
|
Abstract
|
|
|
|
Acetyl-11-ketopomolic acid methyl ester (VI), mp 276-278o, was synthesized from pomolic acid (III). The mild alkaline treatment of VI induced the opening of ring E on carbon skeleton to yield VII, and then VII was deacetylated to give VIII, mp 82-84o. Compound VIII was established as 11, 19-diketo-18,19-secoursolic acid methyl ester. The E-ring opening was believed to be due to retrograde aldol condensation.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|